I went to my 1st Convention last year and it's fully mobility impaired friendly. I use a walking stick and can't move that fast and there were plenty of wheelchair users there too and there were ramps and lifts all over for the event areas. They also operate a 'blue badge' system where people with disabilities were admitted to the larger auditoriums first so they could get settled in suitable places (end of rows, near the front etc).
It's the Hilton Birmingham right next to the NEC, so it's a top flight international standard hotel and consequently it ain't exactly cheap but the discounted room rate (B&B) is actually v. good value, although the beer's not too great - we have a breakout plan to a good local pub in the offing however...