This might have already been done at some point but.... Who would you like to see team up in a DiscWorld novel? I would like to see Vimes and Weatherwax get together and solve some crimes.
The Assassin's Guild and the Fool's Guild, so we can all die laughing. Or maybe not, clowns are scary enough as it is, without the added dimension of being paid to kill you.
A sort of "Charlie's Angels" team sent out at the direction of an unseen controller (Vetinari?) to discreetly and deniably tackle little problems... I'm thinking of an Assassin (Alice Band?) a Thief (Conina?) a witch (One of the young Lancre School?) and a Watchwoman (Angua, Sally or Cheery?) who between them would have all the skills and expertise to sort out "Charlie"'s problem...